GAIN-OF-FUNCTION, FOCAL SEGMENTAL GLOMERULOSCLEROSIS TRPC6 MUTATION MINIMALLY AFFECTS SUSCEPTIBILITY TO RENAL INJURY IN SEVERAL MOUSE MODELS

Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models

Mutations in TRPC6 are a cause of autosomal dominant focal segmental glomerulosclerosis in humans.Many of these mutations are accel lifetime horse supplement known to have a gain-of-function effect on the non-specific cation channel function of TRPC6.In vitro studies have suggested these mutations affect several signaling pathways, but in vivo stud

read more


O-20 MOLECULAR AND BIOLOGICAL CHARACTERIZATION OF HEPATITIS B VIRUS SUBGENOTYPE F1b CLUSTERS: UNRAVELING ITS ROLE IN HEPATOCARCINOGENESIS

Introduction and Objectives: Hepatitis B virus subgenotype F1b infection has been associated with the early occurrence of hepatocellular carcinoma in chronically infected patients from Alaska and Peru.In Argentina, however, despite the high prevalence of subgenotype F1b infection, this relationship has not been described.This study aimed to unravel

read more

Archetypes of memory and amnesia in South African soap opera

This essay investigates the relationship between memory, or rather amnesia, in the South African context and soap deva curl arc angel opera.South Africa has only recently celebrated ten years of democracy and the past still affects the lives of its inhabitants.The country has undergone far-reaching shifts in its political, economic and cultural par

read more